40 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Hyperviscosity Syndrome ... death Neutropenic Fever ... New-onset back pain ... #differential #
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Diagnosis and Management ... - Activation: Liver ... - DiGeorge Syndrome ... #endocrinology ... #differential #algorithm
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Capillary leak syndrome ... Methotrexate • AIN ... #AKI #Cancer #Oncology ... #Differential #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Alcohol-induced pain ... : Pain in involved ... #oncology #diagnosis ... #differential #
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... abdomen if abdominal pain ... → no immediate treatment ... ICANS: altered level ... , weight gain, hypotension
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Insufficiency, Liver ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... is the main clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... symptoms: - Muscle pain ... - Abdominal pain ... #Diagnosis #Management