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diagnosis hematology management syndrome chemotherapy erythematosus lupus sle systemic toxicology cancer hodgkins immune leukemia lymphoma neurology table toxicities workup adultonset
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Headaches, bone pain, fever ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... - Anti-B2GP1 (aPL ... ) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
Immune Checkpoint Inhibitor Toxicity Main Toxicities: Colitis, Pneumonitis, Skin adverse events, Endocrine dysfunction, Hepatitis, Myocarditis,
Checkpoint Inhibitor Toxicity ... Complications and Treatment ... CheckpointInhibitor #Toxicity ... Table #Diagnosis #Pharmacology ... #Oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... → no immediate treatment ... : - Seen with AML ... (~20 %) and APL ... #Emergencies #Oncology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... diagnosis #management #treatment ... #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
the spleen or liver ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Testicular Cancer - Treatment Related Toxicities Bleomycin, Cisplatin, Etoposide, lfosfamide Tinnitus & Hearing Loss Neurotoxicity Pulmonary Fibrosis Hypotension Nephrotoxicity Skin Hyperpigmentation Hemorrhagic Cystitis Myelosuppression Peripheral Neuropathy Ashley
Testicular Cancer - Treatment ... #chemotherapy #toxicity ... toxicology #Toxicities #pharmacology ... #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... search ANA and aPL ... 9) Unexplained fever ... erythematosus #rheumatology
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