26 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP Syndrome ... child * Severe cases ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... : - Thrombocytopenia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #rheumatology #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... leukopenia, anemia, and thrombocytopenia ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Rheumatology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
production • Treatment ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #Hyperthermia #comparison
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
infections/fevers • Thrombocytopenia ... and petechiae Causes ... index < 2 • EPO Level ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... #diagnosis #hematology ... #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison