14 results
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... loss through the nephron ... Pharmacology #nephrology #conversion ... #loop #thiazide ... #classes
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Differential Diagnosis Algorithm ... tubular transport • Diuretics ... (loop/thiazide) ... #Causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... Differential #Diagnosis #Algorithm ... #causes #potassium
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Medications - Loop ... and thiazide diuretics ... Differential #Diagnosis #Low ... #Magnesium #Table ... Classification #Causes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... - Normal/low ... pressure: Active diuretic ... #causes #urinary
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Hypomagnesemia #Magnesium #Low ... #Causes #Differential
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... acid and most diuretics ... Segments #Function #Pathophysiology ... #Tubules #Table
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... through distal nephron ... • Diabetic nephropathy ... #Causes
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... can be high or low ... Uosm <100): Renal Losses ... differential #diagnosis #table
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... contracted • Loop ... diuretics / Bartter's ... #Causes