10 results
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Acetazolamide, Loop ... Amiloride Site of Action ... Pharmacology #Comparison #Table ... HalfLife #Dosing #Loop ... #Thiazide #CHF
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts: - Alkalosis ... plasma insulin (treatment ... , nasogastric suction ... anhydrase inhibitors, loop ... syndrome (mimics loop
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... • Start with LOOP ... are short acting ... aldosterone states (CHF ... contraction metabolic alkalosis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... +2Cl- Symport (Loop ... the Nonspecific Cation ... Tolvaptan) • Treatment ... #Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Na delivery): CHF ... Elimination (see Table ... (IV loop diuretic ... acetazolamide) - IV loop ... (10g PO tid) - caution
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
Failure (HFrEF) Treatment ... edema then add on loop ... diuretics. ... /ambcarerx #CHF ... Pharmacology #Management #Treatment
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
acid and most diuretics ... limb of Henle's loop ... (TAL) - Active ... Segments #Function #Pathophysiology ... #Tubules #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... : Supportive + diuresis ... diagnosis #comparison #table
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... per day until stable ... Loop diuretics for ... Summary #causes #treatment
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
NS followed by loop ... diuretics • IV ... Inhibits vitamin D conversion ... management #drugs #treatment ... #pharmacology #table