20 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Elevated Liver tests, Low ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Elevated Liver tests, Low ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... fever, fatigue, Nausea ... Urticaria #diagnosis #rheumatology ... #comparison #table
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Diagnosis: • Low ... 300 mg/dL) • Low ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Erythema Annulare Centrifugum (EAC),
This is erythema annulare centrifugum (EAC), one of the “figurate erythemas.” These lesions
patient eats a lot ... Most cases are idiopathic ... drugs, systemic disease ... Centrifugum #EAC #clinical ... #photo #dermatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Disease ... originate from a low-grade ... Viral Infection Clinical ... fatigue, pallor, dyspnea ... hemolytic #anemia #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
early localized disease ... called "Bazin's disease ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Prolonged PT/PTT • Low ... organ damage Clinical ... • Severe Liver Disease ... Treat primary cause ... treatment #management #hematology