28 results
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... • SPS - Sodium ... #Hyperkalemia # ... #pharmacology #table ... #comparison #nephrology
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... Kayexelate #Comparison #Table ... Pharmacology #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... nonspecifically binds ... of aspiration #Potassium ... #pharmacology #table ... #comparison #binders
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... • G-CSF • Hypokalemic ... vomiting) • Low ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... 90 minutes) • Sodium ... LouLectures #Hyperkalemia ... #nephrology
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Low pill burden. ... Low pill burden ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Normal Acid-Base: Low ... @priti899 #Hypokalemia ... Algorithm #causes #potassium ... #low #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... • Cell shift: Hypokalemic ... #urine #potassium ... algorithm #diagnosis #nephrology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
this pump, those sodium ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia ... (or low potassium
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al, Low ... Gitelman's syndrome #Hypokalemia ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium