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diagnosis rheumatology systemic neurology cardiology comparison differential druginduced pharmacology summary activation algorithm allergy ana angioedema anisocoria antifungals antinuclear autoantibodies bradykinin
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... 60-80% - Low ... life-threatening • Treatment ... #Erythematosus
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Demyelinating Syndrome ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Systemic #Lupus ... #Erythematosus ... #rheumatology #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... Erythematosus ( ... 60-80% - Low ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... anti-Smith Ab, low ... Clinical Features ... , lymphopenia, low
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... is clinically suspected ... overlap syndromes ... #erythematosus ... #rheumatology #table
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... erythematosus [ ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... factor level • Low ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... GBS), systemic lupus ... erythematosus ( ... SLE), polymyositis ... myopathy #diagnosis #management
Horner's Syndrome on Physical Exam A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... or induced by treatment ... video highlights how ... #clinical #video ... #physicalexam #neurology
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