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Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... morphologically mature B Lymphocytes ... rnature-appearing lymphocytes ... 500/uL clonal B lymphocytes ... #CLL #Chronic #Lymphocytic
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Chronic Lymphocytic ... Leukemia (CBC with Lymphocytes ... - Monoclonal Lymphocytes ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... Absolute blood lymphocyte ... #CLL #Chronic #Lymphocytic
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes ... the etiology Signs ... endocrinology #symptoms #signs
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... CLL (Chronic Lymphocytic ... Leukemia): • Lymphocytes ... Nodes: • Small lymphocytic ... ) and/or Small Lymphocytic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
prognosis • Nodular Lymphocyte ... cells absent, lymphocyte ... Mixed Cellularity, Lymphocyte ... Rich, Lymphocyte ... Amy Chung, MD, MSc
Peripheral Blood shows a subset of atypical lymphocytes with hairy-like cytoplasmic projection. #Clinical #Path #BloodSmear #Blood #Smear
subset of atypical lymphocytes ... #Clinical #Path
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
• Lymphocytic infiltration ... xeropthalmia) Mouth: • Lymphocytic ... pathophysiology #signs
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Pathogenesis and Clinical ... Sydenham's Chorea Lymphocytes ... pathophysiology #diagnosis #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... erythematosus (SLE) Signs ... Symptoms: - Lymphocyte ... Pathophysiology #Diagnosis #Signs
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