225 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... immunophenotype Clinical ... Vmphocytosis on routine CBC ... hematology #hemeonc #diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Large Granular Lymphocytic ... Leukemia Clinical ... Same morphologic/clinical ... LargeGranular #Lymphocytic ... hemepath #pathology #diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Leukemia (CBC with ... Lymphocytes) ... - Monoclonal Lymphocytes ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... Lymphocytosis on CBC ... surface molecules: CD5 ... #Leukemia #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes ... GravesDisease #pathophysiology ... symptoms #signs #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... auto-reactive B and CD ... Sydenham's Chorea Lymphocytes ... RheumaticFever #pathophysiology ... #diagnosis #signs
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... cells absent, lymphocyte ... Rich, Lymphocyte ... Classification #pathophysiology ... #Hematology #Diagnosis
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Parainfluenza • CD4 ... ) Fungal: • CD4 ... Parasitic: • CD4 ... Primary pulm HTN, Lymphocytic ... HIVAIDS #workup #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... regeneration, diffuse CD8 ... + T lymphocytes ... Polymyositis #PM #Diagnosis ... #Pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... Symptoms: - Lymphocyte ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs