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diagnosis management differential signs hematology rheumatology pathophysiology nephrology infections leukemia oncology causes disease gca hepatology infectiousdiseases radiology syndrome vasculitis workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... onset of symptoms ... ALL Symptoms: ... (Chronic Lymphocytic ... CLL Symptoms: •
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Lymphocytes ... Orange or Hep C Clinical ... with no early symptoms ... #Chronic #Lymphocytic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... immunophenotype Clinical ... uw_IMresidency #CLL ... #Chronic #Lymphocytic
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Early and Late Clinical ... SSX (lymphocytic ... - Remitting, chronic ... • Neurologic ... diagnosis #signs #symptoms
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... common - T Cell ... ~10% - B-Cell ... #differential #algorithm
Myocarditis Diagnosis • Endomyocardial biopsy (gold standard, rarely performed) • Clinical presentation • Cardiovascular MRI Clinical •
performed) • Clinical ... Cardiovascular MRI Clinical ... • Antlviral (lymphocytic ... Immunosuppressants (chronic ... • IVIG (Giant cell
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
life Causes and clinical ... and duration of symptoms ... angioedema Other symptoms ... infiltration (lymphocytes ... Atopic diseases, Chronic
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Pathogenesis and Clinical ... CRP Neuronal cell ... surface targeted -> Cell ... Sydenham's Chorea Lymphocytes ... diagnosis #signs #symptoms
Myocarditis 5 Principles of Myocarditis: 1. Build clinical suspicion 2. Decide on EMBx 3. Manage acute cardiac injury 4. Manage chronic
Build clinical suspicion ... Manage chronic cardiac ... myocarditis Clinical ... Treatment: - Lymphocytic ... unclear - Giant Cell
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Large Granular Lymphocytic ... Leukemia Clinical ... version DDx: - chronic ... Same morphologic/clinical ... LargeGranular #Lymphocytic
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