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clinical ultrasound echocardiogram diagnosis cardiology management pulmonary a4c lung differential algorithm msk abdominal radiology effusion plax aortic sign causes aorta
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology of Tumor Lysis ... TLS) Tumor Cell Lysis ... -> Allantoin (High ... Ca-Phos nephropathy (high
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor Lysis ... immature blasts and high ... rasburicase Tumor Lysis ... Pathophysiology: Lysis ... Spontaneous if high
Hypermagnesemia - Etiologies by Mechanism Renal Failure Excessive Mg Administration - Massive PO intake
Mechanisms - Tumor lysis ... Differential #Diagnosis #High
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
transfusion • Tumor lysis ... Normal, Renin High ... hypoplasia Aldosterone high
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... cytotoxic therapies in high-burden ... treatments) occur in high ... wandering_er #Tumor #Lysis
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH LOW PTH - Hypoparathyroid - Congenital (Pediatric)
Algorithm - Low and High ... Hypomagnesemia HIGH ... Tumor lysis syndrome
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... release due to cell lysis ... reaction - Tumor lysis ... causes #potassium #high
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Rhabdomyolysis • Tumor lysis ... glycosides • High
Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis
Rhabdomyolysis • Tumor Lysis ... Hyperlipidemia • Tumor Lysis
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... Massive tumor cell lysis
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