92 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... Massive tumor cell lysis ... cytotoxic therapy of ALL ... TumorLysis #syndrome #TLS
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology of Tumor Lysis ... Syndrome (TLS) ... Tumor Cell Lysis ... TumorLysis #Syndrome #TLS
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Abnormalities of TLS ... Laboratory TLS ... mg/dL Clinical TLS
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor Lysis ... WBC >100k, + lab signs ... leukapheresis - TLS ... Pathophysiology: Lysis ... #Syndrome #TLS
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Treatment of Clinical TLS ... transfer • Tumor lysis ... MatthewHoMD #TLS ... #Tumor #Lysis #
Beevor's Sign on Physical Exam

Beevor's sign is abnormal upward (cephalad) movement of the umbilicus with truncal
Beevor's Sign on ... Exam Beevor's sign ... The sign been also ... been observed in ALS ... PhysicalExam #clinical #video
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... but can also spontaneously ... leukemia (both ALL ... wandering_er #Tumor #Lysis ... #Syndrome #TLS
Tongue Fasciculations in ALS

Martín Hunter MD @interconsulta

#Tongue #Fasciculations #als #amyotrophic #lateral #sclerosis #neurology #physicalexam #clinical #video
Fasciculations in ALS ... Fasciculations #als ... physicalexam #clinical #video
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... Culprits: ALL, ... above #Tumor #Lysis ... #Syndrome #TLS
Jaw-Jerk Reflex Clonus in ALS

- Neurology Pro - A DDx Tool @ProDdx

#JawJerk #Jaw #Jerk #Reflex #Clonus
Reflex Clonus in ALS ... Reflex #Clonus #ALS ... #clinical #video