14 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... /nephritic syndromes ... the patient have glomerular ... hematuria (RBC casts ... #Algorithm #Nephrology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... Acute interstitial nephritis ... Classification #diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... • Hepatorenal syndromes ... Epithelial cell casts ... Acute Interstitial Nephritis ... #KidneyInjury #Nephrology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
INTRINSIC: - Glomerular ... white blood cell casts ... renal tubular cell casts ... or pigmented casts ... #Injury #AKI #Differential
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... syndrome ("Maltese ... 34t5DgJ #Urinary #Casts
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Approach to Acute Kidney ... require urgent nephrology ... Urinary obstruction, Nephrotoxic ... cases are caused ... for WBCs, RBCs, casts
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Acellular Casts ... acute and chronic kidney ... suggestive of nephrotic ... sydnrome • Pigment ... Urine #Microscopy #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... Acute Kidney Injury ... inhibitors, hepatorenal syndrome ... Acute Interstitial Nephritis ... Differential #Diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... • Interstitial nephritis ... Differential #Diagnosis #nephrology ... #causes