51 results
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Neonatal Jaundice Causes ... of pathologic hyperbilirubinemia ... (1) increased bilirubin ... #Diagnosis #Peds ... #Differential #Workup
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
to Conjugated Hyperbilirubinemia ... - Differential Diagnosis ... non-ICU vs ICU causes ... #direct #bilirubin ... gastroenterology #hepatology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Unconjugated hyperbilirubinemia ... posthepatitis hyperbilirubinemia ... miscellaneous causes ... Classification #diagnosis ... #differential #causes
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Non-hemolytic Disorders of Hyperbilirubinemia ... common hereditary hyperbilirubinemia ... • Unconjugated hyperbilirubinemia ... and stress may cause ... #hepatology #diagnosis
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased Serum bilirubin ... #Workup #Hematology ... #Diagnosis *
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Unconjugated bilirubin ... Laboratory #Testing #workup ... #diagnosis #hematology
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... - Differential Diagnosis ... hyperlipidemia, hemolysis, hyperbilirubinemia ... #Framework #Workup ... #phosphate #nephrology
Differential Diagnosis of Acute Kidney Injury 

#Diagnosis #Nephrology #AKI #Acute #KidneyInjury #Causes #Differential #Workup #Algorithm #Ddxof
Differential Diagnosis ... Kidney Injury #Diagnosis ... #Nephrology #AKI ... #KidneyInjury #Causes ... #Differential #Workup
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
- Differential Diagnosis ... - Unconjugated Hyperbilirubinemia ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hepatology #bilirubinemia
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... osmolarity If cause ... , haptoglobin, bilirubin ... #nephrology #causes