9 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Best indications ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
family history - Medications ... test, ANA (e.g., SLE ... changes), high MCV ... not required in all ... Causes #Workup #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... Malignancies (eg CML ... , ALL) • Solid ... #NonHodgkins #comparison ... #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... DIAGNOSTIC CRITERIA FOR ICL ... #Lymphopenia #ICL ... #diagnosis #hematology ... #Differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... La, anti-Jo-1, SCL ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... some time, let’s see ... honestly, this list ... Algorithm #workup #hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
pattern: • SjS, SLE ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
with drug-induced SLE ... Erythematosus #medications ... #drugs #pharmacology ... #risk #differential ... #diagnosis #rheumatology