43 results
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... cotransporter, K channel, Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... #Diagnosis #Differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... pressure: - Cl ... Hypochloremia #Differential ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... Diagnosis #Algorithm #Nephrology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Syndrome - Causes and Treatment ... transformation (CML ... hyperleukocytosis (AML ... Syndrome #Causes #Differential ... #Diagnosis #Treatment
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
release • ↓ Cl ... syndrome #Mechanisms #pathophysiology ... #nephrology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... Ferritin <100 ng/mL ... Ferritin 100-299 ng/mL ... functional ID) Treatment ... composite endpoint of all-cause
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... alkalosis • Loss of Cl ... Cystic fibrosis Cl ... #differential #