20 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
AcuteKidneyInjury #AKI ... #Nephrology #Pathophysiology ... #Pharmacology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... distal tubule. ↑ Nacl ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... barrtin (recruits Cl ... ascending limb Gitelman ... Thiazide-sensitive Na—Cl ... Defects #Kidney #Nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypertensive: • High Al ... Normotensive: • UCl ... Post-hypercapnia • UCl ... Bartter's syndrome, Gitelman's ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... Bartter Syndrome, Gitelman ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... Bartter Syndrome, Gitelman ... Diagnosis #Algorithm #Nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Bartter - Gitelman ... pressure: - Cl ... secretion - Cl ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Kidney Injury (AKI ... - Urine Na/K/Cl ... Causes of Inpatient AKI ... disease — 21% - AKI ... #Nephrology #Diagnosis
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
release • ↓ Cl ... syndrome #Mechanisms #pathophysiology ... #nephrology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
increase of 44 mol ... #Vancomycin #AKI ... #pharmacology # ... diagnosis #management #nephrology