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diagnosis hematology oncology algorithm ana antibody antinuclear disorders erythematosus lupus patterns sle systemic testing associations blood causes classification cytoplasmic hodgkins
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... SLE): ANA (anti-nuclear ... Anti-cardiolipin (aCl ... Anti-centromere, Scl
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Thalassemia • ACD ... Non-hemolytic: ACD ... #Differential # ... Diagnosis #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antibody Testing - Nuclear ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... CD23, o CML ... Blood #Disorders #hematology ... #Markers #Differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... ) 30-45% Differential ... Erythematosus #Diagnosis #autoantibodies ... symptoms #mimickers #differential ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... changes), high MCV ... anemia (vegan, ... not required in all ... Causes #Workup #hematology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antibody Testing - Nuclear ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... #Patterns #differential ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Myelogenous Leukemia (CML ... blood count with differential ... progression to AML ... Syndromes #diagnosis #hematology
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