73 results
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Drug Rashes - Comparison ... >90% of total skin ... #Drug #Rashes #Comparison ... #Erythroderma #Dermatology ... #Emergency #Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Systemic Symptoms (DRESS ... ) Syndrome Treatment ... , IVIG etc • Skin ... #Syndrome #Treatment ... #Management #dermatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... Tubulointerstitial nephritis • Skin ... Prerenal azotemia • Skin ... Syndrome #SJS #TEN #comparison ... #table #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Systemic Symptoms (DRESS ... Skin involvement ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... #Syndrome #dermatology
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
Gout Management ... Inhibitors #Gout #Management ... #CKD #rheumatology ... #treatment #comparison
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... Parasites Drugs: - DRESS ... Primary: - CML ... #Eosinophilia #Differential ... Diagnosis #Causes #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... Diagnosis #Table #Hematology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... GI, lung, skin), ... Heme malig (AML, CML ... Hypersensitivity (DRESS ... #Eosinophilia #Differential
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic #Myopathy #Comparison ... #Managment #algorithm ... #Rheumatology # ... Differential
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
to hours into treatment ... Raised off of the skin ... Blistering and/or skin ... Drug #Reactions #dermatology ... #clinical #comparison