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diagnosis management algorithm neurology pulmonary syndrome nephrology adrenal calcium cardiology hematology hyperkalemia insufficiency pharmacology renal rhabdomyolysis signs symptoms abg abscess
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... #Causes #differential ... diagnosis #calcium #high ... #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis ... Elevated PTH (High ... Lymphoma: NHL, CML ... Diagnosis #Algorithm #causes ... #endocrinology
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... #Differential # ... Diagnosis #Algorithm #causes ... #potassium #high ... #pathophysiology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Myeloid Leukemia (CML ... Drug-induced • High ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... - Differential ... glycosides • High ... blockers - MCW ... #Differential #
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... PTH - Frankly high ... #workup #differential ... #diagnosis #endocrinology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... and Management Summary ... Causes of Rhabdomyolysis ... urine output: 200 ml ... Rhabdomyolysis #Differential
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Insufficiency Differential ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... insufficiency likely: • High ... Diagnosis #Algorithm #endocrinology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... and Management Summary ... Dermatomyositis) AKI - Pathophysiology ... Dialysis for severe hyperkalemia ... #causes #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... WBC count cause ... Spontaneous if high ... hydration - Hyperkalemia
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