42 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... • Scleroderma renal ... • Severe B12 deficiency ... #schistocytes #differential ... #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
) - Differential ... • Bleeding • Hemolysis ... Renal Disease, Liver ... Chronic Infection) High ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... #Algorithm #Differential ... #Diagnosis #hematology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm
Primary Adrenal Insufficiency:
 • Autoimmune primary adrenal insufficiency
 • Adrenoleukodystrophy,
- Differential ... Adrenoleukodystrophy, genetic disorder ... Isolated ACTH-deficiency ... Insufficiency #Differential ... Workup #Algorithm #endocrinology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... lymphoproliferative disorders ... G6PD deficiency) ... Extravascular #Causes #differential ... #diagnosis #hematology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Lymphoproliferative Disorders ... Myeloid Leukemia (CML ... ) - Hemolytic ... Drug-induced • High ... Diagnosis #Algorithm #endocrinology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... ) - Differential ... Bleed • Hemolysis ... Reticulocytosis • Renal ... • Early Iron Deficiency
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider RBC membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... specifically: iron deficiency ... , hemolysis, hemorrhage ... Chronic inflammatory disorders ... myeloid leukemia (CML
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... ASA) • Renal Disease ... Connective Tissue Disorders ... Algorithm #Causes #Hematology