14 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... for workup, including ... Inflammatory Conditions: Rheumatologic ... Diagnosis #Algorithm #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Pseudotumor - Infectious ... History of Bleeding, Infection ... Fatigue • Acute ... Algorithm #Causes #Hematology ... #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... risk-stratification • Risks: infection ... transformation to acute ... #treatment #hematology ... #oncology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute ... infection • Solid ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... myeloid leukemia (CML ... translocation • Acute ... thrombocythemia • Acute ... Diagnosis #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... changes), high MCV ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Malaise, bleeding, infections ... pain, bleeding, infections ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Rare: DAH, acute ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
e.g., HIV), EBV infection ... Etiology: - Infections ... Malignancies (eg CML ... NonHodgkins #comparison #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... presents as an acute ... Ferritin >500 ng/mL ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology