18 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
B-LNH), solid cancers ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... - Differential Diagnosis ... Algorithm Cervical ... #Algorithm #Causes ... #Hematology #Oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Low or absent NK cell ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... CD13, CD33, CD34, HLA-DR ... CD23, o CML ... Blood #Disorders #hematology ... #Algorithm
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... Inflammation • Cancer ... #Algorithm #Causes ... #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
marrow plasma cell ... Causes of false- ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Vasculitides: Giant Cell ... , Sarcoidosis, HLA-B27 ... : Cancer, Histiocytic ... #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
(MCHL) - Lymphocyte ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... treatment of Hereditary ... SF of >1,000 μg/mL ... #diagnosis #management