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diagnosis hematology differential algorithm causes oncology treatment signs disease pancytopenia workup leukemia neurology thrombocytopenia arthritis chronic classification cll disorders erythematosus
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Marrow Failure Syndromes ... Acquired Aplastic ... #Pancytopenia #Syndromes ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... • Improve the symptoms ... #hematology #diagnosis ... #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Script Signs and symptoms ... Medicine @SCVMCMed #Aplastic ... #management #treatment ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... Sideroblastic anemia ... Non-hemolytic: ACD, Aplastic ... anemia, CKD • ... Differential #Diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes, MCV ... , MCH, MCHC, Serum ... Deficiency • Aplastic ... Anemia • Anemia ... Algorithm #Causes #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... experience some symptoms ... anemia (MCV 80- ... than 150,000 per mcL
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... • Marrow Aplasia ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #treatment #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Normocytic" • Anemia ... Myelodysplastic syndrome ... diagnosis #causes #hematology
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