63 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
Therapeutic Target Levels ... lithium, target levels ... (0.5 - 0.8 ng/mL ... mortality at a higher level ... Ranges #Toxicology #Pharmacology
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Action #Nephron #Pharmacology ... #Nephrology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
probably < 1500ng/mL ... Insufficient blood levels ... Special cases (e.g. renal ... #rheumatology #pharmacology ... #levels #lupus
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... decr of C3 and C4 levels ... /min • <60 mL/ ... TerrierBen #Renal ... Cryoglobulinemic #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... syndrome - Na-K-2Cl ... barrtin (recruits Cl ... receptor Distal renal ... Defects #Kidney #Nephrology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
Spironolactone MCW ... Nephrology @MCW_Nephrology ... #diuretics #pharmacology
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Renal Tubular Acidosis ... = Hyperkalemic Renal ... ↓ Aldosterone level ... uncimchiefs #RTA #Renal ... Diagnosis #Algorithm #nephrology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
pressure incr renal ... edgarvlermamd - Nephrology ... HepatoRenal #Syndrome #Nephrology ... #Management #Pharmacology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
HYPOVOLEMIC • extra-renal ... - burns - fevers ... • renal volume ... nephrotic syndrome • renal ... Workup #Algorithm #Nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
• Increased renal ... Hypoperfusion • Reduced renal ... release • ↓ Cl ... pathophysiology #nephrology