26 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... AcuteKidneyInjury #AKI #Nephrology ... #Pathophysiology ... #Pharmacology
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... Anemia • Hapten (Drug ... Hemolytic #Anemia #differential ... #diagnosis #pharmacology ... #table
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
Spironolactone MCW ... Nephrology @MCW_Nephrology ... #diuretics #pharmacology ... halflife #comparison #table
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Immunosuppression in Transplantation
Induction (I):
 - Basiliximab (Simulect)
 - Alemtuzumab (Campath)
 - Rituximab
 - Anti-Thymocyte Globulin (ATG)
Induction
#Medications #Pharmacology ... #Table #Drugs # ... Maintenance #Management #Nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Agents Subclass, Drug ... #Medications #Pharmacology ... #summary #table ... #nephrology
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
Know" series - Drug ... (0.5 - 0.8 ng/mL ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... barrtin (recruits Cl ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Glomerular Disease: Drug ... Membranous GN, MCD ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology