16 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte ... +, Mg2+, Ca2+, Cl ... Carbonic Anhydrase Inhibitor ... #effects #pharmacology ... #comparison #table
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... CARBONIC ANHYDRASE INHIBITORS ... others SGLT2 INHIBITORS ... #Medications #Pharmacology ... #summary #table
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Proton-pump inhibitors ... Loop and thiazide diuretics ... - Calcineurin inhibitors ... Low #Magnesium #Table ... #Classification
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Carbonic Anhydrase Inhibitors ... some overdoses Inhibitors ... of Na+K+2Cl- Symport ... #Nephrology #Pharmacology ... #Medications #Table
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW ... MCW_Nephrology #diuretics ... #pharmacology # ... halflife #comparison #table
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... • Inhibit Na+ Cl ... Carbonic anhydrase inhibitors ... #Pharmacology #
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... leading to osmotic diuresis ... Contraindications: eGFR < 30 mL ... #Pharmacology # ... DM2 #diabetes #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... Mechanisms of Action: Inhibits ... #Pharmacology # ... DM2 #diabetes #endocrinology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Myeloid Leukemia (CML ... drugs • ACE inhibitors ... Cyclosporine • Diuretics ... Diagnosis #Algorithm #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... are similar to diuretics ... #Pharmacology # ... DM2 #Diabetes #Endocrinology