29 results
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... locations: Wrist, MCP ... • Metabolic syndrome ... • Medications ... Gout #Comparison #rheumatology
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
Raynaud Phenomenon Differential ... Diagnosis: Rheumatologic ... - MCC systemic ... , SLE, Sjogren syndrome ... #Differential
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
100 Dosing: 250 mcg ... increase to 500 mcg ... the use of this medication ... #Roflumilast #Indications ... #Pharmacology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... Thrombocytosis #Platelets #Differential
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Precipitants and Pharmacology ... #Pharmacology # ... medications #causes ... #differential #
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... Best indications ... Measurement #SLE #rheumatology ... #pharmacology #
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... - Asthma - COPD ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #dyspnea #sob #differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Myelodysplastic syndrome ... myeloid leukemia (CML ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
) Low MCV - <80fL ... anemia" High MCV ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes #hematology