13 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... SLE • CLL • APLA ... #Causes #Hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
presented with pancytopenia ... promyelocytes, anemia ... 6.8 g/dL), and thrombocytopenia ... promyelocytic leukemia ... hospitalization and treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... involvement CML ... - infiltrates (anemia ... , thrombocytopenia ... #Hematology #Oncology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... anemia (MCV 80- ... Pancytopenia is ... a decrease in all ... The etiology of pancytopenia
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Chronic Myelogenous Leukemia ... effect following treatment ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... (CML) - Hemolytic ... Anemia - Others ... #Diagnosis #Algorithm
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... #hematology #WBC ... #Leukemoid
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... changes), high MCV ... anemia (vegan, ... not required in all ... ITP, unexplained pancytopenia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... infections/fevers • Thrombocytopenia ... virus (EBV) • Leukemia ... Treatment: ... #oncology #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... CD23, o CML ... #Diagnosis #Algorithm