35 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... ) - Differential ... Renal-centered (ie "MGRS ... MGUS #Differential ... #Diagnosis #hematology
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
of undetermined significance ... (MGUS) Mayo Clinic ... monoclonal #gammopathy #MGUS ... Followup #algorithm #diagnosis ... #management #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
of undetermined significance ... (MGUS) A bone ... , low-risk MGUS ... whom there are no clinical ... Biopsy #algorithm #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... ) MGRS: • Fibrillar ... #Monoclonal #Differential ... #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
(MGUS) - Summary ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... #hematology #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... of undetermined significance ... (MGUS), CLL, Myeloma
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
gammopathy of renal significance ... (MGRS) • Secondary ... Capillary leak syndrome ... Cancer #Oncology #Differential ... #Diagnosis #Classification
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - (Reiter’s syndrome ... should have other symptoms ... #msk #Differential ... #Diagnosis #Algorithm
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
of Undetermined Significance ... (MGUS) Fracture ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... Diagnosis Algorithm ... pattern of spread, B symptoms ... Amy Chung, MD, MSc