32 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... : • Acute or Chronic ... effect following treatment ... malignancy • Iron deficiency
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... : Chronic heart ... functional ID) Treatment ... heartfailure #diagnosis #management
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical ... Malnutrition due to chronic ... hyperparathyroidism Treatment ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Cellular immune deficiency ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... mevalonate kinase deficiency ... Disease #diagnosis #management ... #treatment #rheumatology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential ... Framework and Clinical ... Manifestations Causes ... processed grains - Chronic ... beriberi #nutrition #pathophysiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
pneumonia • Chronic ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Lung Abscess Differential ... #causes #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... • Evolution: Chronic ... #Summary #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... thigh bones -> chronic ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology