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diagnosis management rheumatology causes classification neurology syndrome algorithm anemia chronic hemeonc hepatology hodgkins leukemia lymphocytic lymphoma nutrition signs symptoms workup
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... Orange or Hep C Clinical ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... maturation -> Decreased ... BTK -> Impaired maturation ... antibodies) -> Complete deficiency ... Agammaglobulinemia #XLinked #pathophysiology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... immunophenotype Clinical ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... - Protein S deficiency ... considered in all ... Venous #Arterial #pathophysiology ... #hematology #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Cellular immune deficiency ... Unknown cause Treatment
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... mevalonate kinase deficiency ... diagnosis #management #treatment ... #rheumatology
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