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diagnosis causes algorithm extravascular hemolysis hemolytic mcv thrombocytosis approach atlas calculation erythematosus ferritin hyperferritinemia index interpretation key laboratory lupus mds
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Iron deficiency ... , ↓ Ferritin Anemia ... deficiency + Chronic ... #diagnosis #differential ... #hematology #laboratory
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Anemia - Differential ... loss: Intravascular ... #Deficiency #Anemia ... Algorithm #ferritin #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... • PK deficiency ... circulation - Infections ... immune-complex hemolytic anemia ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... G6PD deficiency) ... #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Volume (<80 fL) • Iron ... Inflammation, Chronic Infection ... #MCV #Classification ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Production #Index #hematology ... #anemia #differential
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Microcytic - Iron-deficiency ... , Thalassemia, Iron-deficiency ... , Disseminated intravascular ... key #diagnosis #differential ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... MCH, MCHC, Serum Iron ... Deficiency • ... #Classification ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... inflammation) • Iron ... Macroangiopathic, Infections ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... malignancy • Iron ... deficiency anemia ... Thrombocytosis #Differential
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