15 results
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Iron deficiency ... , ↓ Ferritin Anemia ... deficiency + Chronic ... #diagnosis #differential ... #hematology #laboratory
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Volume (<80 fL) • Iron ... Inflammation, Chronic Infection ... #MCV #Classification ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Production #Index #hematology ... #anemia #differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... MCH, MCHC, Serum Iron ... Deficiency • ... #Classification ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... inflammation) • Iron ... Macroangiopathic, Infections ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... malignancy • Iron ... deficiency anemia ... Thrombocytosis #Differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute infection ... malignancies • Anemia ... (specifically: iron ... deficiency, hemolysis ... Diagnosis #Causes #hematology
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Infection -16% ... Infection - 46% ... Hematologic Malignancy ... Check the iron saturation ... Sideroblastic anemia
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Lactic Acidosis - Classification ... and Differential ... delivery: Hypoxemia, Anemia ... Hepatic failure, Infection ... syndrome, Thiamine deficiency
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
inhibitors and SGLT2 deficiency ... Starvation I - Ingestions ... (rare in lit), iron ... linezolid U - Uremia ... Acidosis #diagnosis #differential