48 results
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Interpretation Iron deficiency ... Ferritin Iron deficiency ... Interpretation #deficiency ... #diagnosis #differential ... #hematology #laboratory
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... • Acute DIC - Septic ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Algorithm for screening/diagnosis and treatment/follow‐up of iron deficiency in patients with chronic heart failure. Hb, haemoglobin;
for screening/diagnosis ... and treatment/follow‐up ... of iron deficiency ... TSAT, transferrin saturation ... #Iron #Deficiency
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Non malignant hematologic ... effect following treatment ... malignancy • Iron deficiency ... #Differential #Diagnosis
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
• Vitamin K deficiency ... • Factor VII deficiency ... elevated in: • Heparin ... Thromboplastin #laboratory #hematology ... #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron deficiency ... Production #Index #hematology ... #differential #diagnosis
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Purpura (TTP) Diagnosis ... severe, ADAMTS13 deficiency ... soon as TTP is diagnosed ... hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... mevalonate kinase deficiency ... splenomegaly • Hepatic ... #management #treatment ... #rheumatology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... Prolonged #Causes #diagnosis ... #differential #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Acute hemolysis, deficiency ... Rebound effect from treatment ... #Differential #Diagnosis