23 results
diagnosis management differential algorithm syndrome anemia aplastic chronic classification lymphocytic mds myelodysplastic thrombocytosis agammaglobulinemia apml arterial basophilia basophils centralretinalartery coagulation
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... -> AML: Blast crises ... phases of maturation ... Phosphorus CLL ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... microglobulin Treatment ... leukemia #CLL ... diagnosis #workup #oncology ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... effect following treatment ... malignancy • Iron deficiency ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... • Folate Deficiency ... ITP • SLE • CLL ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute leukemia ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
total white blood cell ... Chickenpox Other Causes ... : • Iron deficiency ... Differential #Diagnosis #causes ... #hematology #basophils
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... specifically: iron deficiency ... Chronic myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... (CLL) - Summary ... • Most common leukemia ... uw_IMresidency #CLL ... #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... megaloblastic anemia Treatment ... Consider stem cell ... to MDS or acute leukemia ... #hematology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... maturation -> Decreased ... antibodies) -> Complete deficiency ... humoral immunity Signs ... Agammaglobulinemia #XLinked #pathophysiology
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