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causes anemia algorithm management classification hepatology morphology rbc workup agglutinin ana antibodies antinuclear approach arthritis bandemia basophilia basophils biliary bloodcell
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
) Morphology Atlas ... • Microcytic - Iron-deficiency ... #key #diagnosis ... #differential # ... hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... elliptocytosis, Severe iron ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... disorders • Celiac disease ... malignancy • Iron ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... MCH, MCHC, Serum Iron ... Anemia of Chronic Disease ... #Causes #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Diagnosis Algorithm ... Relative - Normal RBC ... #Diagnosis #Algorithm ... #Causes #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... Diagnosis: • ... bile ducts Differential ... #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron ... Chronic kidney disease ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Diagnosis Framework ... inflammation) • Iron ... Spherocytosis, G6PD, PK, HbC ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Diagnosis Framework ... Colitis and Crohn’s Disease ... Other Causes: • Iron ... Irradiation • Cirrhosis ... #hematology #basophils
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... #Bandemia #differential ... #WBC #CBC #hematology ... #pathophysiology
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