22 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... Myelogenous Leukemia ... disorders • Celiac disease ... malignancy • Iron ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... elliptocytosis, Severe iron ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
) Morphology Atlas ... • Microcytic - Iron-deficiency ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Disorders: • Chronic ... Colitis and Crohn’s Disease ... Other Causes: • Iron ... Irradiation • Cirrhosis ... #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... RBCs on Smear • Chronic ... MCH, MCHC, Serum Iron ... Disease • Marrow ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Factor The maturation ... deficiencies: Iron ... kidney disease, ... Production #Index #hematology ... #differential #diagnosis
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
- Differential Diagnosis ... Relative - Normal RBC ... Smoking, Snoring Chronic ... Sleep Apnea • Chronic ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... all phases of maturation ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... cells can indicate disease ... #CLL #Chronic ... #oncology #hematology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
) PSC is a chronic ... asymptomatic at diagnosis ... remain subject to clinical ... #Cholangitis #diagnosis ... management #summary #Hepatology