51 results
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
Diagnosis of active ... CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia ... #Clinical #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... leukocytoclastic vasculitis ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... Differential Diagnosis ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rheumatologic, Vasculitides ... , IBD, Celiac disease ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... cardiac valve, vasculitis ... #Differential #Diagnosis ... Algorithm #workup #hematology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... hypercalcemia) • Anemia ... #Management #oncology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency Anemia ... - Differential Diagnosis ... Structural: Celiac disease ... diet, Alcoholism, Tea-toast ... Algorithm #ferritin #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... 40 ml/min A - Anemia ... chain deposition disease ... Gammopathies #MGUS #diagnosis ... #hematology #oncology