30 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
erythematosus (SLE ... ) Signs / Symptoms ... - Decreased tear ... Xeroderma (Dry skin ... #Diagnosis #Signs
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Antiphospholipid-antibody syndrome ... #rashes #differential ... #diagnosis #rheumatology
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Syphilis Early Primary ... Fever, malaise • Rash ... testing • No symptoms ... lesions in bone, skin ... #signs #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... syndrome (SSS) ... , the differential ... erythematous rash ... #Diagnosis #Dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... Diagnosis Framework ... Primary: 50% ... Secondary: CTD: SLE ... Disease • Cogan syndrome
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... can present with rash ... anti-synthetase syndrome ... Can also see mechanics ... #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... and Symptoms: ... , breast CA - Hematologic ... #diagnosis #dermatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behcet disease) Differential ... Oral aphthae : SLE ... Giant retinal tears ... #signs #symptoms ... #rheumatology #