12 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
syndrome (ST-HUS ... anemia" • HELLP ... syndrome • Catastrophic ... differential #diagnosis #hematology ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... coagulation (DIC) - HELLP ... syndrome - ... uremic syndrome ... #anemia
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... (Hemolysis, Elevated ... Liver tests, Low ... AFLP #obstetrics #hematology ... #diagnosis #table
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... TTP, HUS, DIC, HELLP ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... (Hemolysis, Elevated ... Liver tests, Low ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test ... #anemia #hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Erythematosus Clinical ... Immunologic Criteria CLINICAL ... ANEMIA - LEUKOPENIA ... Direct Coombs’ test ... #Rheumatology #
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
cephalosporin by Test ... carbapenems by Test ... Stevens-Johnson syndrome ... , Hemolytic anemia ... there is a strong clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... with leukopenia, anemia ... Liver function tests ... #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... anemia) • Systemic ... : • Nephrotic syndrome ... (Epstein-Barr syndrome