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diagnosis causes algorithm management clinical nephrology table cardiology pulmonary radiology hematology neurology dermatology ddxof workup pediatrics infections pathophysiology comparison endocrinology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... • Shiga Toxin-Mediated ... - Complement-mediated ... - Metabolism-mediated ... TMA #hematology #differential
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Immunoglobulin E (IgE) mediated ... immunologically mediated ... Nonimmunologically mediated ... #Diagnosis #Differential ... Urticaria #IgE #Mediated
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 Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias - Differential ... smear Immune-mediated ... AHAs) Nonimmune-mediated ... Hemolytic #Anemias #Differential
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Injury (AKI) - Differential ... Interstitial: Immune-mediated ... , Infection-mediated ... Kidney #Injury #Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... Spleen and RES-mediated ... hemolysis - Immune-Mediated ... - Complement-Mediated ... Extravascular #Differential
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... - Shiga toxin-mediated ... - Complement-mediated ... #schistocytes #differential
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
Pathophysiology PTH-mediated ... thyroid Vitamin D mediated ... Lymphomas PTHrp Mediated ... Pathophysiology #Differential
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders - Differential ... - Antibody-mediated ... - Spleen-mediated ... - Infection-mediated ... Platelet #Disorders #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia - Differential ... DAT(+) → Immune mediated ... -) → Infection mediated ... Hemolytic #Anemia #Differential
Infections in Immunocompromised Patients - Differential Diagnosis Summary Innate Immunity: • Neutropenia • Phagocytic Deficiencies • Complement
Immunocompromised Patients - Differential ... Immunity: • Cell-Mediated ... Humoral and cell-mediated ... Immunocompromised #Infections #differential
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