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causes algorithm anemia oncology hemolysis thrombocytopenia classification disorders secondary systemic deficiency eosinophilia medications pancytopenia vasculitis alopecia atlas blood comparison disease
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... atypical HUS) - Drug-induced ... anemia" • HELLP syndrome ... #diagnosis #hematology
Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia #Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
as Triggers of Drug ... Thrombocytopenia #Diagnosis ... #Hematology #Thrombocytopenia ... #Differential # ... DrugInduced #Medications
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... uremic syndrome ... infection) - Drugs ... Extravascular #Causes #differential ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... AIHA: warm, cold, drug ... ABO incompatibility ... classification #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... delayed HTR • Drug-induced ... #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis ... #Differential #
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... , PCH, Evans Syndrome ... #Differential # ... Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... Diagnosis Framework ... -100): • Non-hemolytic ... Orotic aciduria, Drugs ... #Diagnosis #hematology
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