Medication Differential NMS dermatology syndrome anemia clinical rheumatology hemolytic hemolysis workup diagnosis mcv testing aplastic disease chronic hematology agglutinin

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18 results

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

for Hemolysis - ... Intravascular Hemolysis ... Microangiopathic hemolytic ... . primary cold agglutin ... #diagnosis #hematology

Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
- Decreased/NormaI

Corpuscular Volume (MCV ... • Marrow Aplasia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Causes #Hematology

Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
• Thalassemia

-100): • Non-hemolytic ... : ACD, Aplastic ... Hemolytic: ... Non-megaloblastic: Liver disease ... Diagnosis #hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential ... #workup #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #disease #hemolytic ... #anemia #hematology

Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80

) - Differential ... of Chronic Disease ... • Bleeding • Hemolysis ... of Chronic Disease ... #Causes #Hematology

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... #hematology

Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is

kidney disease, ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Eating disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Metastatic Disease ... #Hematology

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