18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... • Marrow Aplasia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
-100): • Non-hemolytic ... : ACD, Aplastic ... Hemolytic: ... Non-megaloblastic: Liver disease ... Diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... malignancies • Anemia ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
) - Differential ... of Chronic Disease ... • Bleeding • Hemolysis ... of Chronic Disease ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential ... #workup #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
kidney disease, ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Eating disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Metastatic Disease ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Eating disorders ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Metastatic Disease ... #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #hemolytic #anemia ... #hematology #diagnosis