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diagnosis causes algorithm hematology hemolytic management high hyperkalemia medications nephrology palpitations pericarditis pharmacology potassium purpura rheumatology acidosis ahus allergy antibiotics
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... #Differential #
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... in Hemolytic Anemia ... #medications #Hemolytic ... #Anemia #differential ... #pharmacology #table
Causes of Palpitations • ARRHYTHMiA • SINUS ARRYTHMIA • ATRIAL FIBRILLATION • ATRIAL
PARKINSON WHITE SYNDROME ... • ILLICIT DRUGS ... SYSTEMIC • ANAEMIA ... Palpitations #Causes #Differential ... #Diagnosis #Cardiology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... infections/fevers • Thrombocytopenia ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... - Antithyroid medications
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... Hemolytic uremic syndrome ... infection) - Drugs ... Extravascular #Causes #differential
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
of Seizures - Differential ... vasoconstriction syndrome ... Toxic: Alcohol, Medication ... , Recreational drugs ... Cerebral Hypoxia, Uremia
Syncope - Differential Diagnosis Algorithm Neurocardiogenic: • Vasovagal • Orthostatic Hypotension • Autonomic Neuropathy • Situational (micturition,
Syncope - Differential ... Hypoglycemia • Anemia ... • Medications ... #Syncope #Cardiology ... #Differential #
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Haemolytic uraemic syndrome ... - Fanconi anaemia ... - Aplastic anaemia ... leukaemia) - Drug-induced ... pediatrics #diagnosis #differential
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... • Metabolic: Uremia ... Dissection, Idiopathic, Drug-related ... Pericardial #Effusion #Differential ... Diagnosis #Causes #cardiology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Secondary Causes: - Drug ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... spotted fever • Drug
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