18 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
hemolytic uremic syndrome ... Adapted from:How to approach ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... Platelet Count - Differential ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint ... trauma (e.g., meniscal ... tears) • Congenital ... Joint #Pain #MSK #rheumatology ... #differential #
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
6mm); • Light-near ... Holmes-Adie Syndrome ... Young females Differential ... - no light-near ... #Adies #Pupil #PhysicalExam
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... Gastrectomy, WHDA syndrome ... diet, Alcoholism, Tea-toast ... Deficiency #Anemia #Differential ... Algorithm #ferritin #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
(Morphological Approach ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Seronegative Reactive Syndrome ... Ligamentous injuries - Meniscal ... Effusions #causes #differential ... diagnosis #msk #physicalexam
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... to the differential ... hemolytic-uremic syndrome ... heart disease, ear ... #Algorithm #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... Inflammation of ear ... #joint #pain #differential ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... tests in Behcet syndrome ... Behcet disease) Differential ... Giant retinal tears ... signs #symptoms #rheumatology