1287 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Folate Antagonist (methotrexate ... Algorithm #Causes #Hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
change disease • Hematologic ... Crystal nephropathy: Methotrexate
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
pyrimethamine and methotrexate ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g. methotrexate ... differential #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
/- intrathecal methotrexate ... Treatment #management #hematology
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Disease Activity - Methotrexate ... management #treatment #rheumatology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Intrathecal (IT) methotrexate ... protection: • IT methotrexate ... mercaptopurine, Weekly oral methotrexate ... pneumonia, IT methotrexate ... L-Asparaginase, IT methotrexate
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
18 percent) - Methotrexate ... #Differential #Hepatology
JAK Inhibitors in 2019

Role in the therapeutic strategy in 2019
 • RA: 2nd line after failure
• Superior to methotrexate ... combination of methotrexate ... #Indications #Rheumatology
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate 
 - Hemodynamically stable 
 - No
Pregnancy with Methotrexate ... examination #Methotrexate