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Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... Toxin-Mediated HUS ... (ST-HUS) • Atypical ... HUS (aHUS) ... Primary #Thrombotic #Microangiopathy
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... entities, but has ... #Thrombotic #Microangiopathy ... HemolyticUremicSyndrome #HUS
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... TTP (atypical HUS ... ), Shiga-toxin HUS ... #Thrombotic #Microangiopathy ... diagnosis #ttp #hus
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolytic-uremic syndrome (ST-HUS ... known as atypical HUS ... Drug-induced thrombotic microangiopathy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mechanical Trauma (Microangiopathic ... - Thrombotic microangiopathy ... uremic syndrome (HUS
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Schistocytes: Microangiopathic ... DIC, TTP, HUS)
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
TMA: Thrombotic microangiopathy ... HUS), Serum creatinine ... HUS) Treatment
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Consumption: - Microangiopathy ... : DIC, TTP, HUS
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Schistocytes DAT(-) → Microangiopathic ... hemolytic anemia (TTP, HUS
Thrombotic Microangiopathy (TMA) - Diagnosis and Management Algorithm #Thrombotic #Microangiopathy #TMA #Diagnosis #Management #Algorithm #hematology
Thrombotic Microangiopathy ... #Thrombotic #Microangiopathy
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